Novel maytansinoid derivatives with peptide linker and conjugates thereof

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专利权人:

IMMUNOGEN INC.

发明人:

WIDDISON WAYNE C.

申请号：

NZ61826212

公开号：

NZ618262A

申请日:

2012.06.21

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Disclosed is a cell-binding agent-cytotoxic agent conjugate represented by the following structural formula as disclosed in the abstract drawing, wherein the different embodiments of the conjugate are as disclosed in the specification. Further disclosed is the use of said conjugate in the manufacture of a medicament for the treatment of cancer.

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