A differential voltage sensing method for achieving input impedance matching comprises the steps of: providing a first bio-potential signal to a first variable resistor for generating a first signal; providing a second bio-potential signal to a second variable resistor for generating a second signal; differentially amplifying first and second signals for generating a third signal; selecting an operation band of the third signal for generating first and second logic signals; and dynamically adjusting one of the impedances of the first and second variable resistors according to the first and second logic signals, wherein each of the first and second bio-potential signals has a common signal voltage level and a differential signal voltage level.