A dental floss pick is composed of a frame, a floss and a grip portion, wherein the frame has a first section and a second section. The first section extends from one end of the frame to a predetermined range and the second section extends from the first section to connect one end of the grip portion. Because the first section defines a first tooth-accommodating area with a height, which is smaller than a distance between the occlusal surface and the interdental papilliae, therefore, when a user places the floss into the slits between the teeth, the floss is limited in depth by the first tooth-accommodating area to avoid damaging the gum. Moreover, the floss is modified into two sections with different materials and shapes for cleaning different teeth slits at different location and characteristics to improve the cleaning convenience and avoid gun injury.
