Preparation of pharmaceutically acceptable salts, and their use as Pharmaceuticals as modulators of chemokine receptor CXCR7.Claim 1: a compound of formula (1) where X represents nr u2075, and represents chry where ry represents Hydrogen or alkyl, c u2081 u208b u2083； and r u00b3 u1d43 and r u00b3 u1d47 along with the carbon Atom to which they are United to form a carbonyl group or two of r u00b2 u1d43, r u00b2 u1d47, r u00b3 u1d43 and r u00b3 u1d47 Dike Wondering whether Hydrogen or alkyl c u2081 u208b u2083； and the rest of r u00b2 u1d43, r u00b2 u1d47,R u00b3 u1d43 and r u00b3 u1d47 represent chrx where X represents Hydrogen； or RX represents Hydrogen, alkyl or c u2081 u208b u2083, and represents nr u2075； and r u00b2 u1d43 and r u00b2 u1d47 along with the carbon Atom to which they are United to form a carbonyl group or two of r u00b2 u1d43, r u00b2 u1d47, r u00b3 u1d43 and r u00b3 u1d47 represent Independent DID c u2081 u208b u2083 Hydrogen or alkyl； and the rest of r u00b2 u1d43, r u00b2 u1d47,R u00b3 u1d43 and x represents Hydrogen or r u00b3 u1d47 represent； and nr u2075 and represents a direct link r u00b2 u1d43 both represent and r u00b2 u1d47； Hydrogen； and r u00b3 u1d43 r u00b3 u1d47 both represent and x represents Hydrogen or nr u2075 represents, and - C (o) -； and r u00b2 u1d43, r u00b2 u1d47, r u00b3 u1d43 and r u00b3 u1d47 all represent Hydrogen or X； Represents a - C (o) -, and represents nr u2075 r u00b2 u1d43； and,R u00b2 u1d47 r u00b3 u1d43 and r u00b3 u1d47 all represent Hydrogen； r u2075 c u2081 u208b u2086 represents alkyl； c u2081 u208b u2084 alkoxy alkyl substituted once with c u2081 u208b u2083, cyano, Vinyl, etinilo,C u2081 u208b u2083 - or alkoxy carbonyl； Co r u00b9 u2070 where r u00b9 u2070 represents alkyl alkoxy c u2081 u208b u2085； c u2081 u208b u2085； phenyl phenyl -； Oxy； phenyl alkyl phenyl alkyl c u2081 u208b u2083； c u2081 u208b u2083 - Oxy； cicloalquil c u2083 u208b u2086 alkyl c u2081 u208b u2083； alquenoxi c u2083 u208b u2084；
