The present invention relates to a pharmaceutical composition comprising at least one liposome and a therapeutic agent for treating a disease due to reduced bone density or cartilage loss with a high drug to lipid ratio and encapsulation efficiency. The pharmaceutical composition improves the pharmacokinetic profile and sustains the release of the therapeutic agent. Also provided is the method for treating a disease due to reduced bone density or cartilage loss using the pharmaceutical composition disclosed herein.本發明關於一種具有高藥物脂質比及高包埋效率的藥物組合物，所述藥物組合物包含至少一微脂體及一用於治療因骨密度降低或軟骨損失導致之疾病的治療劑。所述藥物組合物改善藥物動力學圖譜及維持治療劑的釋放。本發明亦提供使用本文所揭露的藥物組合物用於治療因骨密度降低或軟骨損失導致之疾病的方法。
