HILL, OLIVER,GIEFFERS, CHRISTIAN,THIEMANN, MEINOLF,SCHNYDER, TIM
申请号:
CA2984350
公开号:
CA2984350A1
申请日:
2016.05.04
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Provided herein are specific CD40 receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a CD40L-associated disease or disorder. The CD40 receptor agonist proteins provided herein comprise three soluble CD40L domains and an Fc fragment. The CD40 receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.