The present disclosure provides compositions and dosage forms comprising sinetirucallol, and methods of using such compositions, such as to treat an inflammation-associated disease, liver fibrosis, wound healing, and/or an autoimmune disease. In some embodiments, the composition comprises a Spiranthes sinensis extract.本發明提供包含sinetirucallol之組合物與製劑,以及此類組合物之使用方法,例如用於治療發炎相關疾病、肝纖維化、傷口癒合及/或自體免疫疾病。在許多實施態樣中,前述組合物包含一綬草萃取物。