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METHOD FOR PRODUCING A FIBRIN-BASED BIOARTIFICIAL, PRIMARILY ACELLULAR CONSTRUCT, AND THE CONSTRUCT ITSELF
专利权人:
MEDIZINISCHE HOCHSCHULE HANNOVER
发明人:
Thomas APER,Mathias WILHELMI,Axel HAVERICH
申请号:
US15740247
公开号:
US20180200404A1
申请日:
2016.07.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to a method for producing a bioartificial and primarily acellular fibrin-based construct, wherein a mixture of cell-free compositions containing fibrinogen and thrombin is applied to a surface and subsequently pressurised. An additional aspect of the invention is directed to such fibrin-based bioartificial acellular constructs obtained according to the invention, with improved biomechanical properties, as well as to the use of same in the field of implantology, cartilage replacement or tissue replacement.
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