The U.S.A; as represented by the Secretary ; Department of Health and Human Services
发明人:
Larry W. Kwak,Bira Arya
申请号：
US14268949
公开号：
US20140234362A1
申请日:
2014.05.02
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a vaccine for increasing the immunogenicity of a tumor antigen thus allowing treatment of cancer, as well as a vaccine that increases the immunogenicity of a viral antigen, thus allowing treatment of viral infection, including immunodeficiency virus (HIV) infection. In particular, the present invention provides a fusion protein comprising a defensin fused to either a tumor antigen or viral antigen which is administered as either a protein or nucleic acid vaccine to elicit an immune response effective in treating cancer or effective in treating or preventing viral infection.
