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Production et profilage d'anticorps thérapeutiques dérivés de la technologie HuCAL GOLD entièrement humains spécifiques à la protéine humaine CD38
专利权人:
MorphoSys AG
发明人:
申请号:
EP14196972.5
公开号:
EP2860192A2
申请日:
2006.10.12
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention provides a human antibody that is specific for CD38. The antibody of the invention has the ability to bind to CD38 of minipig origin and induce, by cross-linking, specific killing of cells, in particular tumor cells, expressing CD38. The invention further provides uses of this antibody for treating various disorders and conditions associated with undesired presence of CD38+ cells, including hematological and inflammatory diseases. The invention also provides diagnostic compositions and methods based on detecting the presence of CD38 in a tissue or a cell of minipig origin contacted with the antibody of the invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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