GOEDJE OLIVER,BOHN MATTHIAS,HUNZIKER PATRICK,MOROZOV OLEKSII,FRIEDRICH FELIX
申请号：
IN7809/DELNP/2015
公开号：
IN2015DN07809A
申请日:
2015.08.31
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Apparatus and methods for calculating cardiac output (CO) of a living subject using applanation tonometry measurements. In one embodiment the apparatus and methods build a nonlinear mathematical model to correlate physiologic source data vectors to target CO values. The source data vectors include one or more measurable or derivable parameters such as: systolic and diastolic pressure pulse pressure beat to beat interval mean arterial pressure maximal slope of the pressure rise during systole the area under systolic part of the pulse pressure wave gender (male or female) age height and weight. The target CO values are acquired using various methods across a plurality of individuals. Multidimensional nonlinear optimization is then used to find a mathematical model which transforms the source data to the target CO data. The model is then applied to an individual by acquiring physiologic data for the individual and applying the model to the collected data.
