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Sialylated antigen-specific antibodies for treatment or prophylaxis of unwanted inflammatory immune reactions and methods of producing them
专利权人:
Marc Ehlers
发明人:
Marc Ehlers,Constanze Hess,Alexandra Katharina Lorenz,André Winkler
申请号:
US13260727
公开号:
US20120058111A1
申请日:
2010.03.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to a sialylated isolated antibody specific for an antigen selected from autoimmune antigens, allergens, MHC molecules or Rhesus factor D antigen, comprising an Fc-portion of IgG type, and exhibiting a sialic acid residue at the Fc-portion for use in treatment and/or prophylaxis of autoimmune disease, allergy, transplant rejection or Rhesus factor D reactivity and to methods of producing such an antibody.
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