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INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING ALPHA-V-BETA-3
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
GOODNOW, ROBERT ALAN, JR.,HAMILTON, MATTHEW MICHAEL,KOWALCZYK, AGNIESZKA,SIDDURI, ACHYUTHARAO
申请号:
CA2856619
公开号:
CA2856619A1
申请日:
2013.01.22
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to compounds of formula (I): wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula (I) for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to alpha-V-beta-3 integrin antagonists to target cells expressing alpha-V-beta-3.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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