MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG
发明人:
STEFAN KRUEGER,SIMON GOODMAN
申请号：
BRPI0813513
公开号：
BRPI0813513A2
申请日:
2008.07.17
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The invention relates to a combination therapy for the treatment of tumors and tumor metastases comprising administration of integrin ligands, preferably integrin antagonists, together with co-therapeutic agents or therapy forms that have synergistic efficacy when administered consecutively with said ligands, such as chemotherapeutic agents and or radiation therapy. The therapy results in a synergistic potential increase of the inhibition effect of each individual therapeutic on tumor cell proliferation, yielding more effective treatment than found by administering an individual component alone, concurrently or not in the dosage regime of the present invention.
