Roger Smith,Jacques Dumas,Gan Wang,Wendy Lee,Karl Miranda
申请号：
US12158524
公开号：
US08580798B2
申请日:
2006.12.20
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Substituted pyrimidine derivatives of formula (I), salts, metabolites, prodrugs and diastereoisomeric forms (both isolated stereoisomers and mixtures of stereoisomers) thereof (wherein A=pyrimidine) pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with other active ingredients, e.g., cytotoxic therapies.
