The present invention relates to an antimicrobial composition comprising: (a) a cationic antiseptic selected from the group consisting of biguanides, bisbiguanides, polymeric quaternary ammonium compounds； silver and its complexes； small molecule quaternary ammonium compounds, or combinations thereof； (b) an antimicrobial lipid antiseptic comprising at least one of a (C7-C14)saturated fatty acid ester of a polyhydric alcohol, a (C8-C22)unsaturated fatty acid ester of a polyhydric alcohol, a (C7-C14)saturated fatty ether of a polyhydric alcohol, a (C8-C22)unsaturated fatty ether of a polyhydric alcohol, an alkoxylated derivative thereof, and combinations thereof, where the alkoxylated derivative has less than 5 moles of alkoxide per mole of polyhydric alcohol, and with the proviso that for polyhydric alcohols other than sucrose, the esters comprise monoesters and the ethers comprise monoethers, and for sucrose the esters comprise monoesters, diesters, or combinations thereof, and the ethers comprise monoethers, diethers, or combinations thereof.
