INC.;EXCALIARD PHARMACEUTICALS, INC.;NORTHWESTERN UNIVERSITY;EXCALIARD PHARMACEUTICALS;ISIS PHARMACEUTICALS, INC.
发明人:
DEAN, NICOLAS, M.,MUSTOE, THOMAS, A.,SISCO, MARK,KRYGER, ZOL,BENNET, FRANK, C.
申请号:
EP09812035
公开号:
EP2334319A4
申请日:
2009.08.26
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
This invention provides a method for reducing hypertropic scarring resulting from dermal wound healing in a subject in need which comprises administering to the subject an antisense oligonucleotide which inhibits expression of connective tissue growth factor (CTGF) in an amount effective to inhibit expression of CTGF and thereby reduce hypertrophic scarring.