For lasting immune response induction human acquired immunes deficit syndrome, (AIDS patient is by human immunodeficiency virus (HIV), autoimmune disease, cancer, inflammation, daily management and neurodegenerative disease, including to patients single tablet, rapidly dissolving film, the composition for releasing immediately naltrexone of capsule, liquid or lotion dosage includes about 0.Naltrexone between 01 to about 10. Be conducive to naltrexone must release composition to include about 0. to provide one kind01 about 10 milligram of naltrexone