drug infusion device (10A) is a cylindrical body the drug is filled with (12), and insertable pusher in the hollow portion of the cylindrical body (12) (14), the pusher (14) and which can be displaced filling member in the axial direction (16) for. Filling member (16) has a pusher head portion inserted in a liquid-tight manner into the hollow portion of the tubular body at the distal end side than (14) (12) (42). By retracting the filling member (16) relative to the tubular body (12), the filling of the drug to the tubular body (12), the head unit is moved forward by rotating the pusher (14) by moving the (42) in the distal direction, ejecting the medicament filled in the tubular body (12) from the medicine discharge port (12a).薬剤注入具(10A)は、薬剤が充填される筒状体(12)と、筒状体(12)の中空部に挿入可能な押し子(14)と、押し子(14)に対して軸線方向に変位可能な充填部材(16)とを備える。充填部材(16)は、押し子(14)よりも先端側で筒状体(12)の中空部に液密に挿入されるヘッド部(42)を有する。充填部材(16)を筒状体(12)に対して後退させることにより、筒状体(12)内への薬剤の充填を行い、押し子(14)を回転操作して前進させてヘッド部(42)を先端方向に移動させることにより、筒状体(12)内に充填された薬剤を薬剤吐出口(12a)から吐出する。