A drive device of an infusion syringe piston drive head for moving an infusion syringe piston is described. The device includes an advancing means including an advancing slide, an advancing spindle and a multi-part advancing spindle nut having at least one radially movable nut shell, and a blocking means adapted to be automatically triggered by a control sensor for blocking an infeed motion of the drive head in which the advancing slide is drivable by the advancing spindle nut at the advancing spindle and in which the drive head is arranged at the advancing slide, wherein the blocking means adapted to be automatically triggered by a control sensor includes the multi-part advancing spindle nut for blocking the infeed motion of the drive head on the advancing spindle.
