Emilie Flora Aurore DELAVENNE,Daniel Jean Jacques SIMON,Morten Otto Alexander SOMMER,Rasmus Vendler TOFT-KEHLER
申请号：
US16899812
公开号：
US20200306269A1
申请日:
2020.06.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosam-ide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenesGrain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appear-ance of resistant mutants compared to commonly used topical antibiotics.
