Thomas E. Smithgall,Lori Ann Emert-Sedlak,Billy W. Day,Jielu Zhao,Prema Chandrasekhar Iyer
申请号：
US14441475
公开号：
US20150291534A1
申请日:
2013.11.06
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed herein are embodiments of a compound capable of treating HIV. In particular disclosed embodiments, the compound is capable of inhibiting Nef, such as by acting as antagonists of HIV Nef function. Also disclosed are embodiments of a method of making the compound, embodiments of a method of using the compound, and embodiments of a method of identifying HIV Nef antagonists. The disclosed compound may be used alone or in combination with other pharmacologically active agents in order to promote reducing drug resistance and/or cumulative toxicity.
