WALDSTREICHER, JONATHAN REUBEN,KRIMSKY, WILLIAM SANFORD,TAYLOR, KEVIN JAMES,TUROVSKIY, ROMAN,NEAL, ROBERT E., II
申请号：
CA3087183
公开号：
CA3087183A1
申请日:
2018.12.26
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Methods, systems and devices are provided which transmit energy to a body lumen or passageway in the form of pulsed electric fields (PEFs) and in a manner which provides focal therapy. In some embodiments, PEFs are delivered through independent electrically active electrodes of an energy delivery body, typically in a monopolar fashion. Such delivery concentrates the electrical energy over a smaller surface area, resulting in stronger effects than delivery through an electrode extending circumferentially around the lumen or passageway. It also forces the electrical energy to be delivered in a staged regional approach, mitigating the effect of preferential current pathways through the surrounding tissue. Focal delivery of PEFs can provide increased tissue lethality by employing precise timing and sequencing of energy delivery to the electrodes.
