A system and method for assessing tissue properties of a subject within a region of interest (ROI) using a magnetic resonance imaging (MRI) system includes acquiring chemical-shift-encoded imaging data of the ROI. The method also includes determining, from imaging data a proton density water fraction (PDWF) map and quantifying, using the PDWF map, a property of tissue within the ROI. The method further includes generating, using the PDWF map, a report indicating the quantified property of the tissue. The tissue may include fibroglandular tissue (FGT).
