KOPPAKA VISH,VELLARD MICHEL CLAUDE,OKHAMAFE AUGUSTUS O,ARAYA KIDISTI
申请号：
IN691/DELNP/2013
公开号：
IN2013DN00691A
申请日:
2013.01.22
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof methods of producing and purifying GALNS, and its use in the diagnosis prophylaxis or treatment of diseases and conditions including particularly lysosomal storage diseases that are caused by or associated with a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis rVa (MPS IVa or Morquio A syndrome).
