TWEDEN, Katherine S.,WAATAJA, Jonathan J.,DONDERS, Adrianus P.,KNUDSON, Mark B.
申请号：
AU2015202725
公开号：
AU2015202725A1
申请日:
2015.05.20
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
#$%^&*AU2015202725A120150611.pdf#####ABSTRACT A system for treating a gastrointestinal disorder or a condition associated with excess weight of a subject comprises: at least one electrode configured to be implanted within a body of the patient and placed at a vagus nerve, the electrode also configured to apply therapy to the 5 vagus nerve upon application of a therapy cycle to the electrode and an implantable neuroregulator for placement in the body of the patient beneath the skin layer, the implantable neuroregulator being configured to generate a therapy cycle, wherein each therapy cycle comprises: a) a burst of electrical signals having a frequency of at least 1000 Hz, wherein the burst of electrical signals comprises one or more pulses that have a pulse 10 width of about 0.01 milliseconds to about 0.09 milliseconds, a current of about 0.1 to 20 mAmps, wherein each burst is at least 26 milliseconds and includes a delay period between each burst wherein the burst of electrical signal downregulates activity on the nerve b ) an on period of at least 2 minutes c) an off period, wherein the off period is selected to allow at least partial recovery of nerve activity and d ) a total charge of about 10 to 50,000 15 microcoulombs per therapy cycle. 6479886_1 (GHMatters) P92108.AU.1 SARAHVV 20/05/2015wL wU)) > mL U) z z zZ ZI > > > 0 Q) C 2/8
