Leonard Franklin Pease, III,Hamid Ghandehari,Rajasekhar Anumolu
申请号：
US13695827
公开号：
US20130236396A1
申请日:
2011.05.03
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Described herein are nanoparticles produced from recombinant polymers. The nanoparticles are substantially uniform in size, which provides numerous advantages with respect to the delivery of bioactive agents to a subject. Methods for making the nanoparticles are also described herein. In one aspect, the nanoparticles are produced by the method comprising: a. providing a solution comprising one or more recombinant polymer in a solvent b. forming droplets comprising the one or more recombinant polymers and the solvent c. removing the solvent to produce the nanoparticles and d. separating the nanoparticles based on size to produce nanoparticles that are substantially uniform in size. Finally, pharmaceutical compositions composed of the nanoparticles and methods of using the same are also described.
