The United States of America;as represented by the Secretary;Department of Health and Human Services
发明人:
Shashankkumar J. Patel,Nicholas P. Restifo
申请号：
US16754926
公开号：
US20200316122A1
申请日:
2018.10.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided are methods of producing an isolated population of T cells for adoptive cell therapy, the method comprising culturing isolated T cells in vitro in the presence of a p38 mitogen activated protein kinase (p38 MAPK) inhibitor, wherein the T cells have antigenic specificity for a cancer antigen. Also provided are related isolated populations of T cells, pharmaceutical compositions, and methods of treating or preventing cancer in a mammal.
