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OPHTHALMIC EMULSION
专利权人:
ALCON RESEARCH; LTD.
发明人:
KETELSON, HOWARD ALLEN,MEADOWS, DAVID L
申请号:
NZ59995210
公开号:
NZ599952A
申请日:
2010.12.02
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
599952 Disclosed herein is an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aids in delivering a lipid to the ocular surface. Specifically disclosed is an ophthalmic emulsion comprising: water forming an aqueous phase oil forming an oil phase a hydrophilic surfactant a hydrophobic surfactant a charged phospholipid borate and a mucoadhesive galactomannan polymer wherein: the oil phase is in droplets within the aqueous phase and the droplets have an average diameter that is no greater than about 1000 nm, but is at least 10 nm and the borate and galactomannan polymer cooperatively act to form a gel upon instillation of the emulsion in an eye of an individual. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.
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