The present invention relates to a pyridine derivative of formula (1) wherein R1is optionally-substituted C1-6alkyl, optionally-substituted C3-10cycloalkyl, or optionally-substituted 5- to 10-membered saturated or partially-unsaturated heterocyclyl； R2is halogen atom, cyano, C1-6alkyl which may be optionally substituted with the same or different 1 to 3 halogen atoms, C1-6alkoxy which may be optionally substituted with the same or different 1 to 3 halogen atoms, or amino which may be optionally substituted with the same or different 1 to 2 C1-6alkyl； and the bind with broken line is single or double bond, or a pharmaceutically acceptable salt thereof, which is useful as a medicament for treating symptoms in anxiety-related disorder.本發明係關於一種作為焦慮相關疾病之症狀之治療劑有用之式(1)所表示之吡啶衍生物及其製藥學上容許之鹽。 [式中，R1表示可經取代之C1-6烷基、可經取代之C3-10環烷基、或可經取代之5員～10員之飽和或部分不飽和之雜環基；R2表示鹵素原子、氰基、可經同種或不同種之1～3個鹵素原子取代之C1-6烷基、可經同種或不同種之1～3個鹵素原子取代之C1-6烷氧基、或可經同種或不同種之1～2個C1-6烷基取代之胺基；包含虛線之鍵表示單鍵或雙鍵]
