BLANEY, JEFFREY,GIBBONS, PAUL A.,HANAN, EMILY,LYSSIKATOS, JOSEPH P.,MAGNUSON, STEVEN R.,PASTOR, RICHARD,RAWSON, THOMAS E.,ZHOU, AIHE,ZHU, BING-YAN
申请号:
EP09824234
公开号:
EP2348860A4
申请日:
2009.11.02
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention provides JAK kinase inhibitors of Formula Ia, enantiomers, diasteriomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 , R 7 and Z are defined herein, a pharmaceutical composition that includes a compound of Formula Ia and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a JAK kinase activity in a patient.