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POLYMER COATING FOR MEDICAL DEVICES
专利权人:
Cordis Corporation
发明人:
Zhao, Jonathon Z.
申请号:
AU2014200375
公开号:
AU2014200375B2
申请日:
2014.01.22
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2014200375B220150709.pdf#####Abstract A composition comprising crosslinked silane derivatives linked to a surface having at least two functional terminals comprising an epoxide group and a sulfhydryl group, wherein the sulfhydryl group is oxidized to form sulfonic acid which serves as an in situ catalyst for ring opening polymerization in suitable solvent or in bulk, to graft a first lactone polymer layer, and a second polymer layer is at least one of deposited, coated or sprayed on top of the first polymer layer, said second polymer layer having a therapeutic agent contained therein, the total thickness of the composition being in the range of about 0.01 to about 100 micrometers and wherein the weight of the therapeutic agent is in the range from about 0.1 to about 500 micrograms per square centimeter of surface area. 22/01/14,ck21380abstract,2
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