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METHODS OF TREATMENT USING LIPID COMPOUNDS
专利权人:
发明人:
HOVLAND RAGNAR,SKJAERET TORE,FRASER DAVID A
申请号:
IN4136/CHENP/2013
公开号:
IN2013CN04136A
申请日:
2013.05.28
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
121612Methods are disclosed to treat or prevent at least one disease or condition in a subject in need thereof comprising administering a compound of Formula (I): (I) or a pharmaceutically acceptable salt or ester thereof wherein R and R are independently chosen from a hydrogen atom or linear branched and/or cyclic C C alkyl groups with the proviso that R and R are not both hydrogen or a pharmaceutically acceptable salt or ester thereof. Such diseases or conditions may relate to coronary heart disease (CHD) for example atherosclerosis metabolic syndrome/insulin resistance and/or a dyslipidemic condition such as hypertriglyceridemia (HTG) elevated LDL cholesterol elevated total cholesterol elevated Apo B and low HDL cholesterol. The present disclosure further provides for a method of reducing atherosclerosis development. Pharmaceutical compositions comprising a compound of Formula (I) are also disclosed.
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