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Protozoal varying Surface Protein (VSP, for its acronym in English) as Vehicles for Drug Delivery
专利权人:
CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET);UNIVERSIDAD CATOLICA DE CORDOBA;INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE);CENTRE NATIONAL DE LA RECHERCHE
发明人:
HUGO LUJAN,ELIANE PIAGGIO,DAVID KLATZMANN
申请号:
ARP130102433
公开号:
AR093225A1
申请日:
2013.07.08
申请国别(地区):
AR
年份:
2015
代理人:
摘要:
Claim 1: a Therapeutic composition comprising a VSP vehicle and a Therapeutic Agent.Claim 2: the composition of any of claims 1 to 3, where the vehicle VSP is selected from the group consisting of a VSP, a Protein similar to VSP, a fragment of VSP Protein similar to VSP, a Derivative of VSP Protein similar to VSP, or a combination of two or Most of These vehicles VSP.Claim 13: the composition of any of claims 1 to 12, in which the therapeutic Agent is a biological agent. Claim 18: the composition of claim 15, where the bioactive Peptide is an insulin Analogue.Claim 34: a method for Increasing the Resistance of a Therapeutic Agent to Enzymatic degradation, which comprises combining a VSP vehicle and a Therapeutic Agent, where the vehicle VSP can bind to the therapeutic Agent and the combination of the vehicle and to VSP People Therapeutic results in an increase in the resistance to Enzymatic degradation of the therapeutic Agent.Claim 36: a method for Increasing the adhesion of a Therapeutic Agent to epithelial cells of mucous Membranes, which comprises combining a VSP vehicle and a Therapeutic Agent, where the vehicle VSP can bind to the therapeutic Agent.And where the combination of the vehicle and the VSP Therapeutic Agent results in an increase in the adhesion capacity of [] Therapeutic Agent to epithelial cells of the mucosa. Claim 61: a Complex for the Administration of Drugs, characterized in that it comprises at least a VSP vehicle and a Therapeutic Agent.Reivindicación 1: Una composición terapéutica que comprende un vehículo VSP y un agente terapéutico. Reivindicación 4: La composición de cualquiera de las reivindicaciones 1 a 3, donde el vehículo VSP se selecciona del grupo consistente en una VSP, una proteína similar a VSP, un fragmento de proteína VSP o similar a VSP, un derivado de proteína VSP o similar a VSP y una combinación de dos o más de dichos vehículos VSP. Reivindicación 13: La composición de cualquiera de las reivindicaciones de 1 a 12, donde el
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