The present invention relates to the field of medical equipment's technology, and more particularly to a fixing device for soft tissue with an absorbable screw or titanium screw. The fixing device for soft tissue includes a driving device, screw tube and a drive rod. A catheter is arranged around the screw tube by screw thread, and a plurality of absorbable screws or titanium screws are arranged in the catheter. A screw thread structure is formed on a nailed beam of each of the absorbable screws, and a lead spring is arranged on each of the absorbable screws structure. The plurality of absorbable screws or titanium screws are connected in series in the form of head to tail connection and put into the catheter with a spiral groove. The driving rod is driven to rotate by the driving device in use under pulling the trigger; further the absorbable screw or titanium screw can be shot out of the catheter one by one when the laparoscopic hernia repair is performing. The fixing device for soft tissue with the absorbable screw or titanium of the present invention is particularly suitable for laparoscopic hernia repair operations. Furthermore, the fixing device for soft tissue of the present invention has characteristics of anti-adhesion, convenient and reliable operation, and the catheter is a detachable replacement element, so the fixing device can be reused after the catheter is replaced