Joint fixation systems and methods, enabling: drilling one or more major bores in a joint; drilling one or more minor bores in the joint, wherein the one or more minor bores are disposed about a periphery of and partially overlap the major bore(s); and disposing an implant in the major bore(s) and the one or more minor bores, wherein a cross-sectional shape of the implant substantially conforms to a collective cross-sectional shape of the major bore(s) and the one or more minor bores. Prior to drilling the major bore(s) or the one or more minor bores, a portal tube is disposed adjacent to the joint, thereby providing access to and stabilizing the joint. A drill guide tube is disposed concentrically within the portal tube, and a drill guide is disposed concentrically within the drill guide tube. Subsequent to drilling the major bore(s) and the one or more minor bores, an implant guide tube is disposed concentrically within the portal tube.