The present invention relates to a system for administering a poorly-soluble compound to the skin, the system being capable of exerting an excellent effect by stably impregnating the poorly-soluble compound and effectively delivering the poorly-soluble compound into the skin, and the present invention is technically characterized by a microneedle to which microparticles comprising a poorly-soluble compound are added. In addition, the present invention provides a method for administering a poorly-soluble compound to the skin, the method being characterized by using the microneedle.本發明涉及一種難溶性化合物的透皮給藥系統，所述系統能夠穩定地浸漬難溶性化合物，並將其有效地傳遞至皮膚內，從而能夠發揮優秀的效果，其技術特徵在於，所述系統為添加了包含難溶性化合物的微粒子的微針。本發明還提供一種以利用這種微針為特徵的難溶性化合物的透皮給藥方法。
