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Salt of nitrogen-containing heterocyclic compound or crystal thereof, pharmaceutical composition, and FLT3 inhibitor
专利权人:
FUJIFILM Corporation
发明人:
Mizumoto, Shinsuke,Matsumoto, Takuya
申请号:
AU2014335312
公开号:
AU2014335312B9
申请日:
2014.10.15
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention addresses the problem of providing: a compound exhibiting excellent stability and/or solubility and the like, and further improved FLT3 inhibitory activity; and a pharmaceutical composition. The present invention provides a salt or crystal of (S,E)-N-(1-((5-(2-((4-cyanophenyl)amino)-4-(propylamino)pyrimidine-5-yl)pent-4-yne-1-yl)amino)-1-oxopropane-2-yl)-4-(dimethylamino)-N-methylbuto-2-enamide (compound A). This salt or crystal thereof exhibits excellent FLT3 inhibitory activity, and excellent properties as a drug such as storage stability, solubility, or the like; hence, said salt or crystal thereof is useful in treating a disease or a condition pertaining to FLT3. The present invention provides a pharmaceutical composition and an FLT3 inhibitor which contain this salt or the crystal thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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