Application of pressure at an ulnar region or a radial region may be used to facilitate transradial access procedures, reduce occlusion of the radial artery, or both. A non-circumferential tissue compression device includes a base configured to, when on a wrist of a patient, surround at least a portion of the wrist in a non-circumferential configuration, and an expandable member coupled to the base. The non-circumferential configuration is shaped to allow a clinician to fit the tissue compression device onto the wrist, orient the tissue compression device to engage the wrist, and to enable the expandable member to be inflated without becoming disengaged with the wrist. The expandable member is configured to be positioned over, and apply pressure to, an ulnar region, a radial region, or both before, during, and/or after a transradial access procedure.
