ANDY R. JANISCH,TIMOTHY A. PETERSON,KEITH M. DAHMEN
申请号：
US14911029
公开号：
US20160199317A1
申请日:
2014.08.28
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Transdermal drug delivery systems and compositions containing estradiol. The systems and compositions can include levulinic acid in an amount to enhance transdermal permeation of estradiol and a pharmaceutically acceptable carrier. The systems and compositions can optionally include a solubilizing agent and additional permeation enhancers. Pharmaceutically acceptable carriers can include adhesives, particularly acrylate copolymers, gels, creams, ointments, solutions, suspensions, and pastes.
