Senju Pharmaceutical Co., Ltd.;National Center For Child Health And Development
发明人:
申请号：
EP15830033.5
公开号：
EP3178925A4
申请日:
2015.08.07
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
An object of the present invention is to provide a method of inducing pluripotent stem cells to differentiate into clinically applicable retinal ganglion cells. The present invention provides a method for inducing pluripotent stem cells to differentiate into retinal ganglion cells that can be used for clinical application. Such method is a method for producing retinal ganglion cells with elongated axons comprising the following steps: (a) a step of inducing pluripotent stem cells to differentiate into retinal progenitor cells via floating culture； (b) a step of inducing the retinal progenitor cells obtained in step (a) to differentiate into retinal ganglion cells via floating culture； and (c) a step of allowing axons to elongate via adhesion culture of the retinal ganglion cells obtained in step (b).
