The present invention relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle and of (ii) at least one pharmaceutical compound, to be administered to a subject in need of such a pharmaceutical compound, wherein the nanoparticle potentiates the pharmaceutical compound efficiency. The longest dimension of the biocompatible nanoparticle is typically between about 4 and about 500 nm, its absolute surface charge value is of at least 10 mV ( 10 mV ), and its Young modulus is less than 100 kPa. The invention also relates to such a composition for use for administering the pharmaceutical compound in a subject in need thereof, wherein the at least one nanoparticle and the at least one pharmaceutical compound are to be administered in the subject between more than 5 minutes and about 72 hours one from each other.本發明係關於包括(i)至少一種生物相容奈米粒子及(ii)至少一種醫藥化合物之組合之醫藥組合物,該醫藥組合物欲投與需要此醫藥化合物之個體,其中該奈米粒子加強該醫藥化合物效率。該生物相容奈米粒子之最長尺寸通常介於約4nm與約500nm之間,其絕對表面電荷值係至少10mV( 10mV ),且其楊氏模數(Young modulus)小於100kPa。本發明亦係關於用於在有需要之個體中投與該醫藥化合物之此組合物,其中該至少一種奈米粒子及該至少一種醫藥化合物係依彼此間隔介於超過5分鐘與約72小時之間投與該個體。
