Gene transportation medium composition containing polyamidoamine dendron lipid

• 收藏
• 分享

专利权人:

公立大学法人大阪府立大学

发明人:

河野 健司,高橋 俊成

申请号：

JP2005332011

公开号：

JP4962931B2

申请日:

2005.11.16

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

<；P>；PROBLEM TO BE SOLVED: To solve problems that a non-virus vector using a dendron lipid has no stability or specific adsorbency though the vector has high effects of transfection into a cell and is useful. <；P>；SOLUTION: An amino group at the terminal of the dendron lipid is modified with galactose as a ligand to impart functions to be specifically adsorbed on a receptor on the cell surface. The terminal amino group is modified with PEG to reduce the average particle diameter of the vector. Thereby, stability and easiness of utilization are improved. <；P>；COPYRIGHT: (C)2007,JPO&INPIT

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/