Jean-Laurent PAPARIN;Houcine RAHALI;Aurelien SALANSON;Daniel DA COSTA;David DUKHAN;Timothy J. HARTINGH;Izzat RAHEEM;John SCHREIER;Merck Sharp &; Dohme Corp.
发明人:
Jean-Laurent Paparin,Houcine Rahali,Aurélien Salanson,Daniel Da Costa,David Dukhan,Timothy J. Hartingh,Izzat Raheem,John Schreier
申请号:
US16344233
公开号:
US20190262365A1
申请日:
2017.10.20
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Compounds of Formula (I): (Formula (I)) and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.