A suture anchor assembly and methods of use will now are disclosed for the repair of human or animal tissue defects. The suture anchor assembly is capable of being inserted into a tissue such as bone while also being able to create an expanded profile when subjected to a retrograde force. This expanded profile anchors the suture anchor assembly into the tissue by a changing of position or shape of elements of the suture anchor assembly relative to other assembly elements and the tissue. Embodiments of the suture anchor assembly and methods are capable of precisely positioning assembly elements in the tissue to effectively repair the defects. Some embodiments of the suture anchor assembly are configured to allow for a tissue suture to be anchored without having to knot the tissue suture.