Nouveaux stéroides anti-oestrogènes, compositions pharmaceutiques associées et leur mode d'utilisation

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专利权人:

SRI International

发明人:

申请号：

EP10177213.5

公开号：

EP2305694A3

申请日:

1998.12.23

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Novel and anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependant disorders. Preferred compounds have 1,3,5-estratiene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratienes. Therapeutic methods and pharmaceutical compositions are provided as well.

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