UN PROCÉDÉ POUR AUGMENTER LA SOLUBILITE AQUEUSE D'UN ACIDE BISPHOSPHONIQUE OU D'UN BISPHOSPHONATE

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专利权人:

Grünenthal GmbH

发明人:

申请号：

EP16187412.8

公开号：

EP3158867B1

申请日:

2010.07.30

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Novel solution complexes of zoledronic acid are described which give rise to improved properties of zoledronic acid. The invention includes aqueous solution and molecular complexes of zoledronic acid with and optical isomers of asparagine, histidine, arginine and proline as well as pharmaceutical complexes containing them and methods of treatment using them.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/