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ŚRODKI WIĄŻĄCE CD123 I ICH ZASTOSOWANIA
专利权人:
Janssen Pharmaceutica NV
发明人:
GAUDET, FRANCOIS,ATTAR, RICARDO,HARMAN, BENJAMIN C.,LI, YINGZHE,LUO, JINQUAN,MCDAID, RONAN,POMERANTZ, STEVEN C.,TAM, SUSAN H.,TEPLYAKOV, ALEXEY,WHEELER, JOHN,WU, SHENG-JIUN,NEMETH, JENNIFER F.
申请号:
PL15766973
公开号:
PL3189081T3
申请日:
2015.09.03
申请国别(地区):
PL
年份:
2020
代理人:
摘要:
Provided herein are antibodies that immunospecifically bind to CD123. Also described are related polynucleotides capable of encoding the provided CD 123-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to diagnose, treat, or monitor CD123-expressing cancer progression, regression, or stability; to determine whether or not a patient should be treated for cancer; or to determine whether or not a subject is afflicted with CD123-expressing cancer and thus may be amenable to treatment with a CD123-specific anti-cancer therapeutic, such as the multispecific antibodies against CD123 and CD3 described herein.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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