The present invention relates to methods and devices for exchanging gas molecules between a gaseous medium and a liquid medium which are particularly suited for applications such as blood oxygenation in heart-lung machines and gas scrubbing.The method of the invention comprises the following steps:a) providing a liquid medium having a surface tension in the range of from 0.02 N/m to 0.06 N/m,b) providing a gaseous medium,c) providing a membrane on an interface between the liquidmedium and the gaseous medium, wherein the membrane comprisesi) a carrier substrate with through-going openings having a mean diameter in the range from 0.2 µm to 200 µm, and ii) a porous superamphiphobic coating layer with openings having a mean diameter in the range from 0.1 µm to 10 µm, which is provided at least on the substrate surface facing the liquid medium,wherein either the liquid medium or the gaseous medium, preferably the gaseous medium, comprises at least one target gas to be transferred and said membrane is permeable for the at least one gas to be transferred and not permeable for the liquid medium due to the superamphiphobic properties of the membrane surface facing the liquid medium with respect to said liquid medium,d) contacting the gaseous medium with the liquid medium via said superamphiphobic layer for a sufficient time to enrich the liquid or gaseous target medium with the at least one gas to be transferred.
