César Sánchez Reillo;Jose Antonio Salas Fernández;Aaroa Pérez Salas;Francisco Morís Varas;Alfredo Fernández Braña;Carmen Méndez Fernández
发明人:
Aaroa Pérez Salas,César Sánchez Reillo,Alfredo Fernández Braña,Carmen Méndez Fernández,Jose Antonio Salas Fernández,Francisco Morís Varas
申请号：
US12989778
公开号：
US08598132B2
申请日:
2009.04.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Glycosylated indolocarbazoles, method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates to the methods used to obtain the recombinant strains and the production of rebeccamycin and staurosporine derivatives. The invention also relates to bacterial strains that are of use for the production of rebeccamycin and staurosporine derivatives. Lastly, the rebeccamycin and staurosporine derivatives described herein are applicable to the field of human health, specifically for manufacturing drugs that are of use in the treatment of tumour, neurological and inflammatory diseases.
